Skin cells and proteins dating online
That helps the bacteria travel throughout the cells.“It kind of abuses that system to activate Rac and penetrate the skin,” Winge said.
That’s how Rac1 works in healthy people—or people who get healthy as soon as they recover from their bout with strep. Peter Marinkovich, winner of a 2011 Translational Grant from NPF—studied how Rac1 works in psoriasis, they noticed some important differences.
But it can also be triggered by a strep infection deep inside your throat.
And even though you see it on your skin, your doctor might recommend treating it with pills or injections.
In this new method, which is the first in the world, a human protein called laminin is combined with human skin cells in the laboratory to grow new skin, researchers from Duke-NUS Medical School and Singapore General Hospital (SGH) said on Thursday (Nov 1). As the protein comes from humans, it would likely not pose any risk of infections or adverse immune reactions in patients, unlike the current 40-year-old method of combining mouse cells with human skin cells to grow new skin, said Professor Karl Tryggvason from Duke-NUS Medical School's Cardiovascular and Metabolic Disorders Programme.
Another explanation has to do with the immune system and how it interacts with the skin.“The other reason you could think why Rac1 would be persistently high would be that you have the keratinocytes stimulated in an abnormal way by immune cells,” Winge said.If successful, the new method could potentially be used to treat any kind of burns and other skin defects like chronic wounds, said Dr Chua, who is also an adjunct assistant professor of Duke-NUS Medical School's Musculoskeletal Sciences Academic Clinical Programme.